Coomb’s Test, Indirect

The Indirect Coombs Test, also called the indirect antiglobulin test (IAT), is a laboratory test used to detect antibodies present in a patient’s serum that can bind to red blood cells (RBCs). It is primarily employed in prenatal screening to identify maternal antibodies that may cause hemolytic disease of the newborn (HDN) and in pre-transfusion testing to prevent incompatible blood transfusions. The test involves incubating patient serum with donor RBCs and adding antihuman globulin (Coombs reagent) to detect sensitization. A positive result indicates the presence of clinically significant antibodies, guiding safe transfusion or pregnancy management.


  • Reports On : With 4 Hours
  • Sample Type : Blood
  • Fasting : Not Required