The Direct Coombs Test (Direct Antiglobulin Test, DAT) is a diagnostic blood test used to detect antibodies or complement proteins attached directly to the surface of red blood cells (RBCs). It is primarily used to investigate hemolytic anemia, including autoimmune hemolytic anemia, hemolytic disease of the newborn, and transfusion reactions. During the test, a patient’s RBCs are mixed with anti-human globulin (Coombs reagent). If antibodies or complement are present on the RBC surface, agglutination occurs, indicating a positive result. The test helps identify immune-mediated RBC destruction, guiding further clinical management and treatment decisions.

• Reports On : With 8 Hours
• Sample Type : Blood
• Fasting : Not Required